The need for a better understanding of vectorial epidemiology of malaria transmission in North-central Nigeria, a pre-requisite for effective control, informed this study. The study elucidated seasonal dynamics of biobehavioural ecology of the principal vector of malaria in the area, i.e., Anopheles gambiae s.l., in relation to the species potentials for disease transmission. Adult female mosquitoes were collected bi-weekly, from locations typical of the ecotypes of North-central Nigeria, using all-night human landing catches. Mosquito collections were made both indoors and outdoors during the seasonal periods identified namely, dry, transition and rainy seasons. The wing length of the mosquitoes was measured as a proxy for adult body size. Immature Developmental rates and insecticide susceptibility of the mosquito species were evaluated during the peak of each seasonal period, following standard WHO procedures. Significant (P<0.05) seasonal variations in vectorial attributes were exhibited by An. gambiae in the area. The species was most abundant in the rainy season and least encountered during the dry period. While the mosquitoes were significantly exophagic during dry and transition seasons (56.22 and 63.50% respectively), they showed no such locational feeding preference during the rainy season. Analysis of hourly biting density of the mosquitoes indicated that they were not active during the first half of the night (i.e., 1700 – 2400hrs), both indoors and outdoors, during the transition season. However, while outdoor human biting activity was most intense during the early part of the second half of the night (i.e., 2400 - 0300hrs)in the rainy season, indoor hourly biting density varied within narrow limits in the dry season. While, immature survival rates were generally high (>80%) and insignificantly different (P>0.05) in all seasons, duration of development ranged significantly from 9.40±2.45 days in the dry season to 11.20±2.67 days in rainy. Also, significantly smaller mosquitoes (mean wing length = 2.94±0.36mm) were encountered in the dry season. The adult mosquitoes were susceptible to permethrin insecticide in all seasons, unlike the larval stage that indicated potential resistance during transition and rainy seasons. The findings of this study revealed that seasonal influence plays significant roles in vectorial dynamics of malaria transmission in North-central Nigeria, thus, providing requisite information for fine-tuning malaria vector control strategy for year-round optimum efficacy.